37year old patient with abdominal distension and fever

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CASE PRESENTATION:

A 37 year old female patient house wife by occupation came with chief complaints of abdominal distension and fever from 5days.

HOPI:

Patient was apparently asymptomatic 5days ago then developed Abdominal distension and fever 5days back. Low grade intermittent fever not associated with chills and rigors.

H/O abdominal distension from 5days insidious onset gradually progressing.

H/O polyuria and generalised weakness 

No H/O chest pain , palpitations,jaundice,melena, pedal edema , giddiness.

PAST HISTORY:

4 years ago patient had complaints of jaundice and pain abdomen for one month , usg abdomen was done which showed altered echo texture of liver , gross splenomegaly with multiple vascular channels at splenic hilum , mild ascites, right minimal pleural effusion .

She underwent splenectomy for which no records were available and the patient or her attenders were not clearly explained about the need for splenectomy.

Not a known case of HTN and DM.

PERSONAL HISTORY:

Normal appetite 

Adequate sleep 

Addictions:toddy drinker

Mixed diet

GENERAL EXAMINATION:

Patient is conscious coherent co-operative Oriented to time,place and person

Moderately nourished and moderately built.

VITALS:

Patient is afebrile

BP :160/100mm hg

Pulse rate : 72bpm regular 

RR : 22 cpm

SYSTEMIC EXAMINATION:

Per abdomen - distended.

CVS: S1 S2 Heard no murmurs 

RS: BLAE present NVBS 

CNS : No abnormality detected 

INVESTIGATIONS :

5/11/2020









Aptt-30secs

6/11/2020

Peripheral smear:

RBC- anipoikilocytosis with microcytes , tear drop cells , pencil forms , target cells and schistocytes.

WBC - neutrophilic leucocytosis

PLATELETS- adequate 

IMPRESSION - Microcytic hypochromic anemia with neutrophilic leucocytosis

SEROLOGY - Negative 

ASCITIC FLUID ANALYSIS 

Serum albumin-2.8gm/dl

Ascitic albumin - 0.31gm/dl

SAAG - 2.49

LDH - 41.3IU/L

Amylase - 11.1IU/L

Sugar - 91mg/dl 

Protein-0.5gm/dl

Fundoscopy - normal fundus no KF Ring seen on slit lamp examination 

2D ECHO:

Mild mitral regurgitation, mild triicuspid regurgitation with PAH 

Trivial aortic regurgitation 

No RWMA

No AS, MS

Good LV Systolic function and no diastolic dysfunction.

USG Abdomen:

Impression- chronic liver disease 

Cholelithiasis

Gross ascites 

Left kidney grade 1 RPD changes.

DIAGNOSIS:

ASCITES SECONDARY TO CHRONIC LIVER DISEASE 

SEVERE ANEMIA , DENOVO HYPERTENSION.

TREATMENT:

Day 1

Fluid restriction less than 1.5lit per day

Salt restriction less than 2.5gm/day

Tab lasilactone 20/50 PO OD 

Tab nicardia 20mg PO STAT

Vitals,input and output monitoring

Day 2 

Fluid restriction less than 1.5lit per day

Salt restriction less than 2 gm per day

Tab lasicactone 20/50 PO OD 

INJ zofer 4mg IV SOS

INJ pantop 40mg IV OD 

Vitals monitoring 

Day 3

Fluid restriction less than 1.5lit per day

Salt restriction less than 2 gm per day

Tab lasicactone 20/50 PO OD 

INJ zofer 4mg IV SOS

INJ pantop 40mg IV OD 

Tab rifagute 550mg PO BD

SYP Hepamerz 10ml PO BD 

Tab Cilindepine 10mg PO OD







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